Research in the division covers a wide variety of topics within immunology and integrates closely with the Division of Laboratory Genomics and Medicine to broaden its scope and community. They used computer modeling to accurately predict 75% of effective neoantigens and eliminate 98% of ineffective mutant proteins in melanoma and a common type of lung cancer. Washington University School of Medicine. Washington University School of Medicine. Division of General Medicine. This evaluation resulted in a nearly perfect score, earning â¦ The multicenter study was led by co-senior author Chris Maher of the Oncology Division and investigators at the University of California, San Francisco. Division of Basic Research. Division of Rheumatology John T. Milliken Department of Medicine Washington University School of Medicine Mailing Address: 660 S. Euclid Ave., CB 8045 | St. Louis, MO 63110 Office Location: 4921 Parkview Place, 5th Floor, Suite C | St. Louis, MO 63110 Phone: 314-286-2635 Fax: 314-286-2338 Cisplatin-Associated Neuropathy Characteristics Compared With Those Associated With Other Neurotoxic Chemotherapy Agents (Alliance A151724), Support Care Cancer 2021 Feb;29(2):833-840, Nanoparticle T-Cell Engagers as a Modular Platform for Cancer Immunotherapy, Leukemia 2021 Jan 21; [Epub ahead of print], Intracellular Arginine-Dependent Translation Sensor Reveals the Dynamics of Arginine Starvation Response and Resistance in ASS1-Negative Cells, Immunotherapy and Immunotherapy Combinations in Metastatic Castration-Resistant Prostate Cancer, Renal Failure Among Multiple Myeloma Patients Utilizing Carfilzomib and Associated Factors in the "Real World", Ann Hematol 2021 Jan 21; [Epub ahead of print], Efficacy of Perioperative Chemotherapy for Resectable Pancreatic Adenocarcinoma: A Phase 2 Randomized Clinical Trial, JAMA Oncol 2021 Jan 21; [Epub ahead of print], Phase I Basket Study of Taselisib, an Isoform-Selective PI3K Inhibitor, in Patients With PIK3CA-Mutant Cancers, Clin Cancer Res 2021 Jan 15;27(2):447-459, Rethinking Immune Checkpoint Blockade: 'Beyond the T Cell', A Phase I Trial Evaluating the Effects of Plerixafor, G-CSF, and Azacitidine for the Treatment of Myelodysplastic Syndromes, Leuk Lymphoma 2021 Jan 19:1-14; [Epub ahead of print], Palbociclib and Cetuximab in Cetuximab-Resistant Human Papillomavirus-Related Oropharynx Squamous-Cell Carcinoma: A Multicenter Phase 2 Trial, Oral Oncol 2021 Jan 16;114:105164; [Epub ahead of print], MSIsensor-Ct: Microsatellite Instability Detection Using CfDNA Sequencing Data, Brief Bioinform 2021 Jan 18; [Epub ahead of print], Outcomes of Patients With Single-Node Metastasis of Human Papillomavirus-Related Oropharyngeal Cancer Treated With Transoral Surgery, JAMA Otolaryngol Head Neck Surg 2021 Jan 1;147(1):16-22, Phase 1 Dose Escalation Trial of Volasertib in Combination With Decitabine in Patients With Acute Myeloid Leukemia, Daratumumab in Transfusion-Dependent Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes, Am J Hematol 2021 Jan 15; [Epub ahead of print], Utilization of Radiation Therapy in Multiple Myeloma: Trends and Changes in Practice, Ann Hematol 2021 Jan 12; [Epub ahead of print], Biology of Disease Relapse in Myeloid Disease: Implication for Strategies to Prevent and Treat Disease Relapse After Stem-Cell Transplantation, J Clin Oncol 2021 Jan 12:JCO2001587; [Epub ahead of print], Pemetrexed Maintenance With or Without Pembrolizumab in Non-Squamous Non-Small Cell Lung Cancer: A Cross-Trial Comparison of KEYNOTE-189 Versus PARAMOUNT, PRONOUNCE, and JVBL, Zika Virus Oncolytic Activity Requires CD8+ T Cells and Is Boosted by Immune Checkpoint Blockade, MOMENTUM: Momelotinib Vs Danazol in Patients With Myelofibrosis Previously Treated With JAKi Who Are Symptomatic and Anemic, Future Oncol 2021 Jan 11; [Epub ahead of print], Evaluating the Therapeutic Potential of ADAR1 Inhibition for Triple-Negative Breast Cancer, Proteogenomic Insights Into the Biology and Treatment of HPV-Negative Head and Neck Squamous Cell Carcinoma, Cancer Cell 2021 Jan 5; [Epub ahead of print], Adjuvant Therapy With EGFR Tyrosine Kinase Inhibitors: Tempering Great Expectations With Realism, J Clin Oncol 2021 Jan 8:JCO2003297; [Epub ahead of print], Conservation of Copy Number Profiles During Engraftment and Passaging of Patient-Derived Cancer Xenografts, Circulating Tumor Cells and Biomarker Modulation With Olaratumab Monotherapy Followed by Olaratumab Plus Doxorubicin: Phase Ib Study in Patients With Soft-Tissue Sarcoma, Racial and Age-Related Disparities in Early Mortality Affect the Outcomes of Multiple Myeloma Patients, NCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021, J Natl Compr Canc Netw 2021 Jan 6;19(1):16-27, CC Chemokine Receptor 2-Targeting Copper Nanoparticles for Positron Emission Tomography-Guided Delivery of Gemcitabine for Pancreatic Ductal Adenocarcinoma, ACS Nano 2021 Jan 6; [Epub ahead of print], RON Signalling Promotes Therapeutic Resistance in ESR1 Mutant Breast Cancer, Intratumoral Injection of Clostridium Novyi-NT Spores in Patients With Treatment-Refractory Advanced Solid Tumors, Defining Phenotypic and Functional Heterogeneity of Glioblastoma Stem Cells by Mass Cytometry, JCI Insight 2021 Jan 5; [Epub ahead of print], Understanding the Organ Tropism of Metastatic Breast Cancer Through the Combination of Liquid Biopsy Tools, Integration of the Drug-Gene Interaction Database (DGIdb 4.0) With Open Crowdsource Efforts, Nucleic Acids Res 2021 Jan 8;49(D1):D1144-D1151, Nanoparticle Albumin-Bound Paclitaxel Plus Carboplatin Induction Followed by Nanoparticle Albumin-Bound Paclitaxel Maintenance in Squamous Non-Small-Cell Lung Cancer (ABOUND.sqm): A Phase III Randomized Clinical Trial, Overall Survival of Patients With Triple-Class Refractory Multiple Myeloma Treated With Selinexor Plus Dexamethasone Vs Standard of Care in MAMMOTH, Successful Administration of Sequential TVEC and Pembrolizumab Followed by Temozolomide in Immunotherapy Refractory Intracranial Metastatic Melanoma With Acquired B2M Mutation, Treatment of Acute Renal Vein Thrombosis With Direct Oral Anticoagulants: A Case Series, Am J Ther 2020 Dec 29;Publish Ahead of Print; [Epub ahead of print], Heparin-Induced Thrombocytopenia in a Patient With Coronavirus Disease-19: Diagnostic and Management Challenge, CARM1 Regulates Replication Fork Speed and Stress Response by Stimulating PARP1, Mol Cell 2020 Dec 30; [Epub ahead of print], Phase Ib Study of Enzalutamide With or Without Sorafenib in Patients With Advanced Hepatocellular Carcinoma, SARS-CoV-2 Infection Induces Long-Lived Bone Marrow Plasma Cells in Humans, Incidence of Metastatic Prostate Cancer on the Rise, Oncology (Williston Park) 2020 Dec 7;34(12):522-534, Enhanced Efficacy and Increased Long-Term Toxicity of CNS-Directed, AAV-Based Combination Therapy for Krabbe Disease, Mol Ther 2020 Dec 31; [Epub ahead of print], Proteomic Resistance Biomarkers for PI3K Inhibitor in Triple Negative Breast Cancer Patient-Derived Xenograft Models, Impact of Bronchiectasis on Incident NTM Pulmonary Disease: A 10-Year National Cohort Study, Spatial Heterogeneity in and Distributional Characteristics of Rural Ecological Livability in China--The Case of Fujian Province, Integrated Proteogenomic Characterization Across Major Histological Types of Pediatric Brain Cancer, The Assessment of Convalescent Plasma Efficacy Against COVID-19, VLA4-Nanoparticles Hijack Cell Adhesion Mediated Drug Resistance (CAM-DR) to Target Refractory Myeloma Cells and Prolong Survival, Clin Cancer Res 2020 Dec 22; [Epub ahead of print], Upregulation of 5'-Terminal Oligopyrimidine mRNA Translation Upon Loss of the ARF Tumor Suppressor, Antibody Profiling of Patients With Prostate Cancer Reveals Differences in Antibody Signatures Among Disease Stages, Hormonal Modulation of ESR1 Mutant Metastasis, Oncogene 2020 Dec 15; [Epub ahead of print], The Use of Serial Circulating Tumor DNA (CtDNA) to Detect Resistance Alterations in Progressive Metastatic Breast Cancer, Clin Cancer Res 2020 Dec 15; [Epub ahead of print], A Systematic Framework to Rapidly Obtain Data on Patients With Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance, Clin Genitourin Cancer 2020 Dec;18(6):423-424, Immunity, Immunotherapy, and Rectal Cancer: A Clinical and Translational Science Review, Transl Res 2020 Dec 8; [Epub ahead of print], Real-World Outcomes of Patients With Locally Advanced or Metastatic Epithelioid Sarcoma, Hepatic Epithelioid Hemangioendothelioma Associated With Acute Disseminated Encephalomyelitis by a Possible Paraneoplastic Process, Rare Tumors 2020 Nov 25;12:2036361320977012, PD-L1 Blockade in Combination With Inhibition of MAPK Oncogenic Signaling in Patients With Advanced Melanoma, Therapeutic Plasma Exchange for Iatrogenic Hypertrigylceridemia, Multiple Myeloma, Version 3.2021, NCCN Clinical Practice Guidelines in Oncology, J Natl Compr Canc Netw 2020 Dec 2;18(12):1685-1717, Successful Use of BRAF/MEK Inhibitors as a Neoadjuvant Approach in the Definitive Treatment of Papillary Craniopharyngioma, J Natl Compr Canc Netw 2020 Dec 2;18(12):1590-1595. 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